Precision Pharmacotherapy: Unveiling the Types, Necessity and Application of Targeted Drug Delivery

Abstract

Targeted drug delivery systems have emerged as a promising approach to enhance the efficacy and reduce the side effects of therapeutic agents. The primary objective of targeted drug delivery systems is to selectively deliver therapeutic agents to specific sites within the body, such as tumours or inflamed tissues, while minimizing systemic exposure. This is achieved through the incorporation of targeting ligands, such as antibodies, peptides, or small molecules, which can recognize and bind to specific receptors or biomarkers expressed on the surface of target cells. These systems offer advantages such as improved pharmacokinetics, prolonged circulation time, and enhanced cellular uptake. Additionally, they can be engineered to respond to stimuli present in the microenvironment of diseased tissues, allowing for controlled drug release at the target site. The article also highlights recent developments in the field, such as the use of nanotechnology for precise drug delivery, the application of gene editing techniques for targeted therapy, and the integration of imaging modalities for real-time monitoring of drug delivery.